WHITE BLOOD CELL ENZYMES
WBCs in peripheral blood samples retain enzymatic
activity and can alter substrates added in the laboratory. The presence of enzymatic activity is useful in
studying cells that are so morphologically abnormal
on stained smear that it is difficult to determine their
cell line of origin (see Fig. 1–2). The two most
common WBC enzyme tests are the test for leuko-
cyte alkaline phosphatase, an enzyme found in
neutrophils, and the periodic acid–Schiff stain,
which tests for enzymes found in granulocytes and
erythrocytes.
activity and can alter substrates added in the laboratory. The presence of enzymatic activity is useful in
studying cells that are so morphologically abnormal
on stained smear that it is difficult to determine their
cell line of origin (see Fig. 1–2). The two most
common WBC enzyme tests are the test for leuko-
cyte alkaline phosphatase, an enzyme found in
neutrophils, and the periodic acid–Schiff stain,
which tests for enzymes found in granulocytes and
erythrocytes.
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